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Study and development of piezotronic biosensors based on ZnO

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Start date : 1 September 2020

offer n° IMEPLAHC-05152020-CMNE

PhD thesis subject:

Study and development of piezotronic biosensors based on ZnO

IMEP-LaHC / MINATEC / Grenoble-France
Deadline for application: May 31th 2020


Nanotechnologies, Nanowires, Piezoelectricity, Biosensor, Semiconductor Physics and technology.

Description of the project:
Semi-conductor piezoelectric nanowires (NWs) (of GaN or ZnO among others) have improved piezoelectric properties compared to thin films and bulk materials, because of their greater flexibility, their sensitivity to weaker forces, and also, due to an intrinsic improvement in their piezoelectric coefficients which has been identified by recent theoretical and experimental studies [1, 2].
The coupling of piezoelectric polarization and semiconducting properties of the nanostructures allow the design of new “piezotronic” devices with new functionalities and improved performance. They can be used in applications like pressure or strain sensors, biosensors, photodetectors, etc. [3, 4, 5]. In France, the IMEP-LaHC has contributed in this area with the study of several piezotronic devices based in NWs [6, 7].
These studies have been realized in collaboration with different laboratories and research institutes in France and abroad. In this domain, several devices have been explored but very few studies have been reported about their reliability and lifetime.

The objective of this thesis will be the design, study and development of new architectures of biosensors exploiting the piezotronic effect on NWs. The purpose is to develop biosensors with high sensitivity, reliability and lifetime.

The student will have at his disposal all the experimental facilities of the laboratory, as well as access to the PTA technological platform for the preparation of specific test structures (metallization of contacts, connections, etc.).
The NWs will be developed at the IMEP-LaHC or will be accessible through different collaborations.
The surface functionalization and biological manipulations will be realized as well through collaborations (LMGP, INL, Institute Néel, INAC…).

[1] X. Xu, A. Potié, R. Songmuang, J.W. Lee, T. Baron, B. Salem and L. Montès, Nanotechnology 22 (2011)
[2] H. D. Espinosa, R. A. Bernal, M. Minary‐Jolandan, Adv. Mater. 24 (2012)
[3] Y. Zhang, Y. Liu and Z. L. Wang, Advanced Materials 23 (2011)
[4] X. Wang, Am. Ceram. Soc. Bull, 92 (2013).
[5] K. Jenkins, V. Nguyen, R. Zhu and R. Yang, Sensors 15 (2015)
[6] M. Parmar, E. A. A. L. Perez, G. Ardila, E. Saoutieff, E. Pauliac-Vaujour and M. Mouis, Nano Energy 56 (2019)
[7] Y.S. Zhou, R. Hinchet, Y. Yang, G. Ardila, R. Songmuang, F. Zhang, Y. Zhang, W. Han, K. Pradel, L. Montes, M. Mouis and Z.L. Wang, Adv. Mater. 25 (2013)

More information:
Knowledge and skills required:
It is desirable that the candidate has knowledge in one or more of these areas: semiconductor physics, piezoelectricity, clean room techniques and associated characterizations (SEM, etc.), surface functionalization, biosensors.
The grades and the rank as undergraduate and especially for the Master degree are a very important selection criterion for the doctoral school.

IMEP-LaHC / Minatec / Grenoble, France

Doctoral school:
EEATS (Electronics, Electrical engineering, Automatism, Signal processing), specialty NENT (Nano Electronics Nano Technologies).

About the laboratory:
IMEP-LAHC is located in the Innovation Center Minatec in Grenoble. The main research areas concern Microelectronic devices (especially CMOS, SOI), Nanotechnologies, Photonic and RF devices. It works in close partnership with several industrial groups (such as ST-Microelectronics, IBM, or Global Foundries), preindustrial institutes (such as LETI, LITEN, IMEC, or Tyndall), as well as SMEs (e.g. CEDRAT).
The PhD thesis will be carried out within the group working on MicroNanoElectronic Devices /Nanostructures & Nanosystems. The student will have access to several technological (clean room) and characterization platforms.

Gustavo ARDILA  :

  • Keywords : Engineering sciences, Electronics and microelectronics - Optoelectronics, FMNT, IMEP-LaHc
  • Laboratory : FMNT / IMEP-LaHc
  • CEA code : IMEPLAHC-05152020-CMNE
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Circuit partitioning for multi-FPGA platforms

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Start date : 1 September 2020

offer n° SL-DRT-20-0941

FPGAs are currently widely used for integrated circuit prototyping, or developing of hardware computing accelerators such as hardware implementations of deep neural networks. The circuits coming from these thematics can become very large in size and require to be implemented on a platform consisting in multiple tightly-coupled FPGAs.

The Design Environment & Architecture Laboratory of CEA LIST is devoloping, as part of its Prototem software platform for circuit prototyping, a tool for partitioning an electronic circuit described as a hypergraph for execution on a given multi-FPGA platform. It consists in a multi-resource hypergraph partitioner, equivalent to state-of-the-art tools like hMetis or PaToH.

The goal of this thesis is to adapt the academic problem of hypergraph partitioning to the objectives described by the circuit designers. More adapted modelings will have to be studied in terms of established performance criteria, including the cost function. New types of constraints from the profession will have to be integrated. Finally, a static mapping type modeling, taking into account constraints linked to the target platform integrating routing and signal multiplexing issues, will be proposed.

  • Keywords : Engineering sciences, Technological challenges, Mathematics - Numerical analysis - Simulation, New computing paradigms, circuits and technologies, incl. quantum, DACLE, Leti
  • Laboratory : DACLE / Leti
  • CEA code : SL-DRT-20-0941
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Automatic circuit instrumentation for the design of reliable systems

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Start date : 1 September 2020

offer n° SL-DRT-20-0901

Fault tolerant circuits are currently required in several major application sectors and are going to be mandatory in future domains like autonomous vehicles. CAD tools are required to automate the insertion of fault tolerant mechanisms and validate the reliability properties of the circuit. Fault injection emerged as a widely accepted solution for the qualification plan of a design but with various challenges. In particular, the fault propagation analysis is not enough accurate or involves too much overhead in terms of computation time.

The aim of the thesis is the implementation of a CAD tool for the automatic instrumentation of integrated circuits for an efficient fault propagation analysis after fault injection. The instrumentation modifies the circuit by inserting pieces of hardware to provide external controllability and observability of fault effects. Besides fault propagation analysis, the circuit instrumentation allows performing fault detection and error correction during system operation. The candidate must have experience in the design of embedded systems and knowledge of circuit reliability.

  • Keywords : Technological challenges, Emerging materials and processes for nanotechnologies and microelectronics, New computing paradigms, circuits and technologies, incl. quantum, DACLE, Leti
  • Laboratory : DACLE / Leti
  • CEA code : SL-DRT-20-0901
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Integrated Bioelectrodes and Biopolymer-Microneedle Devices for Transdermal Electrochemical Sensing

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Start date : 1 October 2020

offer n° SL-DRT-20-0673

Electrochemical sensors have attracted considerable interest owing to their tremendous promise for portable and rapid monitoring of personal health. Current devices are limited to single analyte detection (mostly glucose) in biofluids over short times using invasive sample collection. In this PhD, we propose to combine electro-enzymatic sensor technology with less-invasive, painless microneedle (MN)-based sampling for rapid detection of different biomarkers (e.g. glucose and nitrate) in interstitial fluid. The goal is to establish a sensitive and convenient platform for analyte detection for better metabolic profiling of diabetes and cardiovascular disease. This PhD project will explore the use of hydrogel-forming microneedles (e.g. saccharide-based) coupled with single/dual bioelectrode systems for signal transduction. The mechanical, structural and sensor properties will be characterised and optimised. Toxicity and in-vivo assays will be performed on rodents with first device prototypes. The PhD. Work will be carried out at DTBS CEA Grenoble in collaboration with Dr. Gross from Dpt. Of Molecular Chemistry (UGA). The applicant should hold a Master degree in Chemistry, with focus on polymer chemistry, biomaterials, or electrochemistry.

  • Keywords : Technological challenges, Health and environment technologies, medical devices, DTBS, Leti
  • Laboratory : DTBS / Leti
  • CEA code : SL-DRT-20-0673
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Waveguide adressing architecture for retinal projection display integration

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Start date : 1 October 2020

offer n° SL-DRT-20-0837

CEA Tech Leti is involved for several years in the development of an original concept of optical device for Augmented Reality applications. This retinal projection display concept is based on advanced technological process: SiN waveguide photonics and holographic printers. The PhD is dedicated to the first technology and concern the design of addressing waveguide architecture. It will be done in continuity of a former ending PhD on the design of dense waveguide networks in the visible range. This network, that has to interact with pixelated holograms, has to be addressed by an array of optical emitters. The PhD student will simulate and develop the waveguide multi-level architecture needed to link the emitters (LED, VCESL, laser array) to the waveguides network. He will also follow the technological steps in the clean room and bring the device characterization. The Phd will end by the conception and realization of a prototype demonstrating the interaction between an optical emitter array and a digital hologram through a waveguide network.

  • Keywords : Engineering sciences, Technological challenges, Optics - Laser optics - Applied optics, Photonics, Imaging and displays, DOPT, Leti
  • Laboratory : DOPT / Leti
  • CEA code : SL-DRT-20-0837
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