Carbon-13 NMR at natural abundance now possible
Categorie(s) : News, Research
Published : 2 June 2014
INAC researchers have leveraged dynamic nuclear polarization, an emerging hyperpolarization technique, and an innovative sample preparation protocol to apply advanced solid NMR techniques to compounds in which carbon-13 is only present naturally, meaning at 1.1%.
This latest advance eliminates the need to use isotopic labelling to track an isotope with a variation—a technique that requires a high degree of sensitivity. And, because the use of isotopic labelling is generally limited to biological molecules, the innovation will open the door to new applications for any material for which X-rays are inadequate.
The research will continue under a project funded by the French National Research Agency (ANR) through 2016.