News : Biochemistry

The overall objective of the project is to propose a new mode of biocatalytic production based on continuous flow and combining macro and micro-fluidics. The aim is to develop a biocatalysis process involving fluidic bioreactors capable of ensuring continuous biotransformation, thanks to immobilized enzymes or whole cell catalysts. This process will be optimized to improve […] >>

With its tuneable chemical reactivity, cysteine plays crucial roles as Ni ligands in active sites of redox Ni enzymes. Instead, histidines are preferred to coordinate Ni(II) ions in non-redox proteins. Interestingly, cysteine exhibits extreme patterns of conservation, being either highly conserved or completely degenerated, with a strong tendency to form buried cysteine clusters. The case […] >>