Real-time, stress-free cell sorting

Categorie(s) : News, Research

Published : 1 October 2012

If you hybridize a macromolecule made of a short oligonucleotide and an antibody on the probes of a DNA chip, you get a cell biochip that can recognize things like cells and bacteria. This is exactly what an innovative research team at INAC recently did to develop a method for capturing blood cells involved in the human body’s immune response. Their unique biochip can also free these specific cells for additional analyses, thanks to restriction sites on the probes’ DNA. In this process the blood cells are not exposed to any chemical, thermal, mechanical, or radiation stress.
The goal of this research is to develop a “bedside” diagnostic tool, but several more years of work lie ahead before the technology will be reliable and cost-effective enough.



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